Allergen

∞ generated and posted on 2016.08.19 ∞

Immune-system stimulating agents particular that result in type I hypersensitivities and associated release of histamine.

Allergens generally are large molecules, such as proteins, that are both foreign to the body and mistakenly recognized by the immune system as dangerous, especially parasitic invaders, which need to be forcibly eliminated via an acute immune response involving particularly the release of the inflammatory signaling molecule, histamine.

Allergens consist predominantly of IgE-binding proteins. This response normally is one that is mounted especially against endoparasites such as helminths.

Common allergens include those associated with dander, dust mites, foods (food allergies including to legumes, peanuts, which are a type of legumes, and shellfish, particularly crustaceans), pets (e.g., cats or dogs), and of course pollen.

Individuals who are genetically predisposed towards sensitivity to allergens are described as possessing an atopic syndrome or atopy. See also the concept of anaphylaxis.


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