Clusters of Differentiation

∞ generated and posted on 2016.03.19 ∞

Glycoprotein differences found on the surface of T cells, especially CD4 and CD8 glycoproteins.

The CD4 glycoproteins are co-receptors associated with T helper cells and the CD8 glycoproteins are co-receptors associated with T cytotoxic cells. These co-receptors interact with major histocompatibility complex class II and major histocompatibility complex class I molecules, respectively.

The CD4 glycoprotein also serves as the viral receptor molecule recognized by HIV, which is why HIV targets, in part, helper T cells.


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