Cross Resistance

∞ generated and posted on 2022.02.08 ∞

Especially a pleiotropy where the different phenotypes associated with a single bacterial allele are those of interference with the infectability of different phage types.

Cross Resistance generally means that resistance is acquired to a selecting phage and this resistance is associated with resistance to another phage type that the bacterium has not necessarily also been exposed to.

Cross resistance is typically seen when two phages share a bacterial surface receptor, one which otherwise, i.e., in the non-mutated form, would be used for virion adsorption.

One can consult a Phage Cocktail Cross-Resistance Avoider app.

See also depth of activity.

Next | Previous phage therapy-related terms: Depth of Activity | Community Resistance.

See Google Scholar for References.