Uptake of extracellular substances by animal cells into vesicles that is mediated by binding of the substance to specific docking proteins that are found on the surface of those cells.
The process of receptor-mediated endocytosis involves the action of the protein termed clathrin, which is involved in the invagination step that results in vesicle formation.
Receptor-mediated endocytosis is responsible, for example, for the uptake of low-density lipoproteins (LDLs) by animal cells.
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