∞ generated and posted on 2022.02.08 ∞
Measure of the potential for a phage cocktail to inhibit the evolution of phage resistance in target bacteria.
| Depth of Activity for a target bacterium is equal to the number of individual phages, sourced from different cross-resistance groups, that are found in a phage cocktail and for which that bacterium is found in their individual host ranges. |
Depth of activity is measured on a per-target bacterium basis, though it is possible to calculate a 'breadth' of depth of activity for a given phage cocktail and collection (panel) of diversity strains of target bacteria.
One can consult a breadth of depth of activity Phage Cocktail Optimizer app.
Contrast with breadth of activity as well as, to a degree, simply spectrum of activity.
Next | Previous phage therapy-related terms: ECOI | Cross resistance.
See Google Scholar for References.