Humanized Antibody

∞ generated and posted on 2016.03.20 ∞

Mouse mAbs that have their constant regions replaced with ones which are recognized by our bodies as self rather than as foreign.

Humanized antibodies are important for artificially acquired passive immunity, particularly where the recipient's immune system comes into contact with the exogenously supplied antibody. In particular, humanized antibodies combine ease of development and production with versatility of use.

See also fully humanized antibody.